75000 - Document - Cover Page
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75010 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS
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75020 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical)
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75030 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (UNAUDITED)
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75040 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (UNAUDITED)
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75050 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
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995455 - Disclosure - Nature of the Business
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Accounting for the Merger
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995485 - Disclosure - Short-Term Investments
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995495 - Disclosure - Pre Funded Warrants
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995505 - Disclosure - Sale of Asset
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995515 - Disclosure - Fair Value Measurements
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995525 - Disclosure - Investment in Equity Securities
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995535 - Disclosure - Property and Equipment, Net
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995545 - Disclosure - Prepaid Expenses and Other Current Assets
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995555 - Disclosure - Accrued Expenses and Other Current Liabilities
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995565 - Disclosure - Restructuring Charges
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995575 - Disclosure - Commitments and Contingencies
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995585 - Disclosure - Debt
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995595 - Disclosure - Convertible Preferred Stock
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995605 - Disclosure - Common Stock
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995615 - Disclosure - Stock-Based Compensation
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995625 - Disclosure - Agreements with Horizon
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995635 - Disclosure - Related Party Transactions
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995645 - Disclosure - Defined Contribution Plan
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995655 - Disclosure - Income Taxes
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995665 - Disclosure - Net Loss per Share
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995675 - Disclosure - Segment Reporting
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995685 - Disclosure - Subsequent Events
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995695 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995705 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995715 - Disclosure - Accounting for the Merger (Tables)
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995725 - Disclosure - Short-Term Investments (Tables)
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995735 - Disclosure - Fair Value Measurements (Tables)
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995745 - Disclosure - Property and Equipment, Net (Tables)
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995755 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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995765 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995775 - Disclosure - Restructuring Charges (Tables)
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995785 - Disclosure - Commitments and Contingencies (Tables)
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995795 - Disclosure - Debt (Tables)
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995805 - Disclosure - Common Stock (Tables)
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995815 - Disclosure - Stock-Based Compensation (Tables)
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995825 - Disclosure - Agreements with Horizon (Tables)
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995835 - Disclosure - Income Taxes (Tables)
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995845 - Disclosure - Net Loss per Share (Tables)
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995855 - Disclosure - Segment Reporting (Tables)
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995865 - Disclosure - Nature of the Business - Additional Information (Detail)
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995875 - Disclosure - Summary of Significant Accounting Policies - Summary of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents (Details)
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995885 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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995895 - Disclosure - Pre-Funded Warrants (Additional Information) (Details)
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995905 - Disclosure - Sale of Asset (Additional Information) (Details)
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995915 - Disclosure - Fair Value Measurements - Schedule of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis (Detail)
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995925 - Disclosure - Investment in Equity Securities - Additional Information (Details)
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995935 - Disclosure - Property and Equipment, Net - Schedule of Property Plant and Equipment (Detail)
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995945 - Disclosure - Property and Equipment, Net - Additional Information (Detail)
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995955 - Disclosure - Prepaid Expenses and Other Current Assets - Summary of Prepaid Expenses and Other Current Assets (Detail)
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995965 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Detail)
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995975 - Disclosure - Commitments and Contingencies Summary of Amounts Reported in the Balance Sheet in Respect of Operating Lease Assets and Corresponding Liabilities (Detail)
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995985 - Disclosure - Commitments and Contingencies - Schedule of Operating Lease Cost and Variable Lease Costs and Sub Lease Income (Detail)
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995995 - Disclosure - Commitments and Contingencies - Schedule of Maturities of Operating Lease Liabilities (Detail)
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996005 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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996015 - Disclosure - Debt - Additional Information (Detail)
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996025 - Disclosure - Debt - Summary of Long-term Debt Balance (Detail)
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996035 - Disclosure - Debt - Summary of Long-term Debt Balance (Detail) 2
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996045 - Disclosure - Common Stock - Schedule of Shares of Common Stock for Future Issuance (Detail)
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996055 - Disclosure - Common Stock - Additional Information (Detail)
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996065 - Disclosure - Stock-Based Compensation - Additional Information (Detail)
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996075 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activity (Detail)
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996085 - Disclosure - Stock-Based Compensation - Company's RSU activity (Details)
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996095 - Disclosure - Stock-Based Compensation - Summary of Assumptions Used to Value Stock Options Granted (Detail)
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996105 - Disclosure - Stock-Based Compensation - Summary of Stock Based Compensation Expense (Detail)
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996105 - Disclosure - Stock-Based Compensation - Summary of Stock Based Compensation Expense (Detail) [Default]
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996115 - Disclosure - Agreements with Horizon - Additional Information (Detail)
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996125 - Disclosure - Related Party Transactions - Additional Information (Detail)
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996135 - Disclosure - Income Taxes - Additional Information (Detail)
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996145 - Disclosure - Net Loss per Share - Summary of Computation of Diluted Net Loss Per Share Attributable to Common Stockholders (Detail)
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996155 - Disclosure - Segment Reporting (Additional Information) (Details)
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996165 - Disclosure - Segment Reporting - Schedule of Segment Reporting Information by Segment (Details)
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Related Party Transaction [Table]
Homology
Homology [Member]
Homology.
Commercial milestone payment payable
Commercial Milestone Payment Payable
Commercial milestone payment payable.
Class of warrants or rights term
Warrants and Rights Outstanding, Term
Accounting Policies [Line Items]
Accounting policies.
Restructuring Charges
Restructuring and Related Activities Disclosure [Text Block]
Milestones payment
Milestones Payment Receivable
Milestones Payment Receivable
Common Stock, Capital Shares Reserved for Future Issuance
Common stock capital shares reserved for future issuance
Share based awards, common stock reserved for issuance
Annual rent operating lease aggregate after increase.
Annual Rent Operating lease Aggregate After Increase
Annual rent operating lease aggregate after increase
Schedule of Accrued Expenses and Other Current Liabilities
Schedule of Accrued Liabilities [Table Text Block]
Preferred Stock, Shares Issued
Preferred stock shares issued
Debt
Debt Disclosure [Text Block]
Total lease liability
Total operating lease liabilities
Total
Operating Lease, Liability
Interest expenses
Interest Expense, Operating and Nonoperating
Pre Funded Warrants Abstract
Pre Funded Warrants Abstract
Lessee, Operating Lease, Liability, to be Paid, after Year Four
Thereafter
Lessee Operating Lease Liability Payments Due After Year Four
Weighted-average grant date fair value, options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value
Weighted- Average Exercise Price, Vested
Non-cash lease expense
Operating Lease, Right-of-Use Asset, Periodic Reduction
Nature Of Business [Line Items]
Nature of business.
Commitments and Contingencies
Commitments and contingencies (Note 10)
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted-average common shares outstanding-diluted
Weighted-average common shares - diluted
Milestone receivable upon the earlier of achievement of the first milestone
Other Receivables, Net, Current
Other Receivables, Net, Current, Total
Components Of In Process Research And Development Expenses [Axis]
Components of in process research and development expenses.
Minimum [Member]
Minimum [Member]
Sale of Asset Guaranteed Upfront
Sale of asset guaranteed upfront.
Sale of asset guaranteed upfront
Vesting of restricted stock, Shares
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Private Placement [Member]
Debt instrument effective rate of interest percentage
Debt Instrument, Interest Rate, Effective Percentage
Series A-1 convertible preferred stock [Member]
Series A-1 convertible preferred stock [Member]
Series A One Convertible Preferred Stock [Member]
Series A One Convertible Preferred Stock.
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock shares outstanding
Investment, Name [Axis]
Pre Funded Warrant Liability
Pre Funded Warrant Liability
Executive insurance reserve
Self Insurance Reserve
Tranche [Domain]
Tranche.
Fair Value, Measurements, Recurring [Member]
Fair Value, Recurring [Member]
Off-Balance-Sheet Credit Exposure, Policy [Policy Text Block]
Off-Balance Sheet Risk
Common stock shares issued
Common Stock, Shares, Issued
Common stock shares issued
Transaction costs related to reverse recapitalization
Transaction costs related to reverse recapitalization
Transaction costs related to reverse recapitalization included in accounts payable and accrued expenses
Segment Reporting [Line Items]
Asset Purchase Agreement [Member]
Asset Purchase Agreement [Member]
Asset Purchase Agreement
Non-Rule 10b5-1 Arr Modified [Flag]
Non-Rule 10b5-1 Arrangement Modified [Flag]
Non-Rule 10b5-1 Arrangement Modified
Provision for income taxes
Total income tax provision
Income Tax Expense (Benefit)
Provision for tax expense (benefit)
Provision for income taxes
Property, Plant and Equipment [Member]
Property, Plant and Equipment [Member]
Sales Agreement [Member]
Sales Agreement [Member]
Horizon collaboration agreement
Horizon Collaboration Agreement [Member]
Horizon collaboration agreement.
Temporary Equity [Member]
Temporary Equity.
Related Party Transaction [Line Items]
Amounts Due Under Asset Purchase Agreement Current
Amounts Due Under Asset Purchase Agreement Current
Amounts due under Asset Purchase Agreement
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units [Member]
Stock Issued During Period, Value, Conversion of Units
Issuance of common stock for conversion of Convertible Notes, Value
Issuance of Common Stock Pursuant to At-the-Market Offering, Net of Discounts and Issuance Costs
Issuance of Common Stock Pursuant to At-the-Market Offering, Net of Discounts and Issuance Costs
Issuance of common stock pursuant to at-the-market offering, net of discounts and issuance costs, shares
Class of warrants or rights number of securities covered by warrants or rights
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Stock Issued During Period, Value, Conversion of Convertible Securities
Conversion of convertible preferred stock to common stock in connection with the Merger, Value
Line of credit maximum borrowing capacity
Line of Credit Facility, Maximum Borrowing Capacity
Less imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Property and Equipment, Net
Property, Plant, and Equipment [Text Block]
Cash Consideration [Member]
Cash Consideration.
Nonoperating Income (Expense)
Total other income
Schedule of Long-Term Debt Instruments [Table]
Entity Addresses, Address Type [Axis]
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
Income Statement [Abstract]
Loss on impairment of equity investment
Loss on impairment of equity investment
Loss on impairment of equity investment
Legacy Q32
Legacy Q32 [Member]
Legacy Q32 [Member]
Schedule of Operating Lease Cost and Variable Lease Costs and Sub Lease Income
Lease, Cost [Table Text Block]
Foreign exchange contracts & other forign heding arrangements [Member]
Foreign Exchange Contracts Option Contracts And Other Foreign Exchange Hedging Arrangements [Member]
Foreign exchange contracts option contracts and other foreign exchange hedging arrangements.
Subsequent Event Considerations
Subsequent Events, Policy [Policy Text Block]
Related and Nonrelated Parties [Domain]
Net loss per share - basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Net income (loss) per share-basic
Document Period End Date
Document Information [Table]
Proceeds from Debt, Net of Issuance Costs
Proceeds from issuance of common stock pursuant to at-the-market offering, net of discounts and issuance costs
Share based awards, maximum contractual term
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Debt Instrument [Line Items]
Weighted- Average Exercise Price, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Common Stock, Shares Authorized
Common stock, shares authorized
Statement of Stockholders' Equity [Abstract]
Business Combination, Contingent Consideration, Asset, Current
Business combination, intial consideration
Total prepaid expenses and other current assets
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Sublease aggregate base rent obligation
Sublease Aggregate Base Rent Obligation
Sublease aggregate base rent obligation.
Foreign Currency Transactions
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Equity Method Investments and Joint Ventures [Abstract]
Equity Method Investment [Abstarct]
Temporary Equity Disclosure [Abstract]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Aggregate Intrinsic Value, Outstanding Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate Intrinsic Value, Outstanding Beginning Balance
Aggregate Intrinsic Value, Outstanding Ending Balance
Total assets
Assets
Net assets acquired
Title of 12(b) Security
Schedule of Equity Method Investments [Line Items]
Preferred Stock, Value, Issued
Preferred stock, $0.0001 par value; 10,000,000 shares authorized, no shares issued and outstanding at September 30, 2026 and December 31, 2025
Related Party Transaction [Axis]
Consulting and Advisory Agreements
Consulting And Advisory Agreements [Member]
Consulting and advisory agreements.
Issuance of common stock from option exercises
Stock Issued During Period, Value, Stock Options Exercised
Tranche [Axis]
Tranche.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Stock-Based Compensation Expense
Share based compensation by share based award options granted during the period shares
Number of Shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Title and Position [Domain]
Antidilutive Securities, Name [Domain]
Waltham Massauchets [Member]
Waltham Massauchets [Member]
Waltham massauchets.
Proceeds from Issuance of Private Placement
Proceeds from issuance of common stock and pre-funded warrants in private placement, net of issuance costs
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Issuance Of Common Stock And Prefunded Warrants In Registered Direct Offering Amount
Issuance Of Common Stock And Prefunded Warrants In Registered Direct Offering Amount
Issuance of common stock and pre-funded warrants in Registered Direct Offering, net of issuance costs
Personnel Related Costs Excluding Stock Based Compensation
Personnel Related Costs Excluding Stock Based Compensation
Personnel-related costs (excluding stock-based compensation)
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Upfront payment made
Upfront Payment Made
Upfront payment made.
Components Of In Process Research And Development Expenses [Domain]
components of in process research and development expenses.
Commitment And Contingencies [Table]
Commitment and contingencies.
Change in fair value of CVR liability
Change In Fair Value Of Equity Investment
Change In Fair Value Of Equity Investment
Cash and Cash Equivalents [Domain]
Weighted Average Remaining Contractual Term, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term
Segment Reporting [Table Text Block]
Schedule of Segment Reporting Information by Segment
Tranche Two [Member]
Tranche Two Milestone [Member]
Tranche two milestone.
Operating lease liability
Increase (Decrease) in Operating Lease Liability
Patent Costs
Patents Costs [Policy Text Block]
Patents costs.
Beginning balance
Ending balance
Equity, Attributable to Parent
Total stockholders' equity
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Income Taxes
Income Tax Disclosure [Text Block]
Bempikibart [Member]
Bempikibart [Member]
Bempikibart [Member]
Earnings Per Share [Text Block]
Net Loss per Share
Number of Reportable Segments
Operating segment
Reserved For Future Issuance Under Two Thousand And Twenty Four Stock Plan Member
Reserved For Future Issuance Under Two Thousand And Twenty Four Stock Plan [Member]
Shares reserved for future issuance under the 2024 Stock Incentive Plan
Stockholders' Equity Note [Abstract]
Sale of Asset
Asset Acquisition [Text Block]
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Beneficially Own Percentage Of Number Of Shares
Beneficially Own Percentage Of Number Of Shares.
Beneficially Own Percentage Of Number Of Shares
Carrying amount
Long-Term Debt
Commitment And Contingencies [Line Items]
Commitment and contingencies.
Stock, Class of Stock [Table]
Line of credit facility outstanding current
Venture debt, current portion
Line of Credit, Current
Restricted Stock [Member]
Restricted Stock [Member]
Disclosure In Tabular Form Of Common Stock Shares Reserved For Future Issuance [Line Items]
Disclosure in tabular form of common stock shares reserved for future issuance.
Disclosure in Tabular form of Common Stock Shares Reserved for Future Issuance [Line Items]
Principal payments on venture debt
Payment On Venture Debt
Payment On Venture Debt
Series B convertible preferred stock [Member]
Series B convertible preferred stock [Member]
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Stock.
Proceeds from Stock Options Exercised
Proceeds from option exercises
Long term debt variable interest rate percentage
Long-Term Debt, Percentage Bearing Variable Interest, Percentage Rate
Geographical [Domain]
Statistical Measurement [Axis]
Office space leased
Area of Real Estate Property
Deferred Transaction Costs
Deferred Transaction Costs
Deferred transaction costs included in accrued expenses and other current liabilities
Money Market Funds [Member]
Money Market Funds [Member]
Entity Interactive Data Current
Restructuring and Related Costs [Table Text Block]
Schedule Of Restructuring Liability Related to the Restructuring Plan
Fair value of options vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Expected stock price volatility range, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Gain (Loss) on Extinguishment of Debt
Gain (Loss) on Extinguishment of Debt, Total
Loss on extinguishment of venture debt
Loss on extinguishment of debt
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term, Vested and expected to vest
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Common stock, $0.0001 par value; 400,000,000 shares authorized, 29,892,127 and 12,858,047 shares issued and outstanding at September 30, 2026 and December 31, 2025, respectively
Common Stock, Value, Issued
Common Stock Value
Nature of the Business
Business Description and Basis of Presentation [Text Block]
Property and Equipment
Property, Plant, and Equipment [Policy Text Block]
Summary of Estimated Useful Life of Assets
Summary Of Estimated Useful Life Of Assets [Table Text Block]
Summary of estimated useful life of assets.
Total liabilities
Liabilities
Unamortized debt discount and issuance costs
Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net
Payroll tax credit.
Payroll tax credit
Payroll Tax Credit
Mergers and Aquisitions Abstract
Mergers and Aquisitions [Abstract]
Schedule of Financial Assets And Liabilities Measured At Fair Value On A Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Product and Service [Axis]
Business Combination, Contingent Consideration, Change in Contingent Consideration, Liability, Increase (Decrease)
Issuance of CVR at fair value
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Convertible Preferred Stock [Member]
Significant Other Unobservable Inputs (Level 3) [Member]
Fair Value, Inputs, Level 3 [Member]
Shares reserved for future issuance under the 2017 Stock Incentive Plan [Member]
Reserved For Future Issuance Under Two Thousand And Seventeen Stock Plan [Member]
Reserved for future issuance under two thousand and seventeen stock plan.
Loss on disposal of property and equipment
Gain (Loss) on Disposition of Property Plant Equipment
Accounts payable
Increase (Decrease) in Accounts Payable
Equity Method Investment, Ownership Percentage
Equity method investment, ownership, percentage
Ownership Percentage
Total operating expenses
Operating Expenses
Issuance of common stock to Homology shareholders in reverse recapitalization, Value
Stock Issued During Period Value to Homology Shareholders Reverse Recapitalization
Stock Issued During Period Value to Homology Shareholders Reverse Recapitalization
Issuance of Common Stock and Pre-Funded Warrants in Private Placement, Net of Issuance Costs
Issuance of Common Stock and Pre-Funded Warrants in Private Placement, Net of Issuance Costs
Issuance of common stock and pre-funded warrants in private placement, net of issuance costs, Shares
Share Price
Offering share price
Receivable from exercise of stock options
Receivable from Exercise of Stock Options
Receivable from Exercise of Stock Options
Stock Issued During Period, Shares, Conversion of Units
Issuance of common stock for conversion of convertible notes, Shares
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Share based awards, vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Issuance of Common Stocks from RSU Vesting
Issuance of Common Stocks from RSU Vesting
Issuance of common stock from RSU vesting, Shares
Tranche One [Member]
Tranche One Milestone [Member]
Tranche One Milestone [Member]
Tranche one milestone.
Class of Warrant or Right, Outstanding
Warrants and Rights Outstanding
Pre-funded warrants to purchase
Restricted Cash And Cash Equivalents Non Current [Member]
Restricted Cash And Cash Equivalents Non Current [Member]
Restricted cash and cash equivalents non current.
Risk-free interest rate range, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Issuance of common stock in the pre-closing financing, Value
Issuance of Common Stock During Period Pre-Closing Net of Issuance Costs
Issuance of Common Stock During Period Pre-Closing Net of Issuance Costs
Series A Redeemable Preferred Stock [Member]
Series a redeemable preferred stock.
Series A Redeemable Preferred Stock [Member]
Less accumulated depreciation
Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization
Nature Of Business [Table]
Nature of business.
Related Party Transactions [Abstract]
Fixed lease costs
Operating Lease, Cost
Long-Lived Tangible Asset
Long-Lived Asset, Class [Axis]
Income Taxes
Income Tax, Policy [Policy Text Block]
Subsequent Events
Subsequent Events [Text Block]
Pre Funded Warrants [Member]
Pre Funded Warrants [Member]
Other General and Administrative Expense
Other G&A expenses
Assets:
Operating Lease Assets Lessee [Abstract]
Operating lease assets lessee [Abstract].
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected stock price volatility range
Determination of Fair Value of Common Stock on Grant Dates
Determination Of Fair Value Of Common Stock On Grant Dates [Policy Text Block]
Determination of fair value of common stock on grant dates.
Property Plant and Equipment [Line Items]
Property, Plant, and Equipment [Line Items]
ATM Offering Program [Member]
ATM Offering Program [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate range
Restructuring Charges [Abstract]
Line of credit remaining borrowing capacity
Line of Credit Facility, Remaining Borrowing Capacity
Percentage of sublicense fees
Percentage Of Sublicense Fees
percentage of sublicense fees.
Schedule of Amounts Reported In The Balance Sheet In Respect Of Operating Lease Assets And Corresponding Liabilities
Disclosure In Tabular Form Of Amounts Reported In The Balance Sheet In Respect Of Operating Lease Assets And Corresponding Liabilities [Table Text Block]
Disclosure in tabular form of amounts reported in the balance sheet in respect of operating lease assets and corresponding liabilities [Table Text Block].
Lease liability, current portion
Operating Lease, Liability, Current
Operating lease liabilities
Disclosure In Tabular Form Of Venture Debt [Table]
Disclosure in tabular form of venture debt.
Collaboration Arrangement
Collaborative Arrangement, Accounting Policy [Policy Text Block]
Received amount from Horizon
Proceeds from Collaborators
Liabilities and Equity
Total liabilities and stockholders' equity
Expected dividend rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
2027
Lessee, Operating Lease, Liability, to be Paid, Year Two
Research and development expenses
Research and development
Research and Development Expense
Research and Development Expense, Total
Document Fiscal Period Focus
Share-Based Payment Arrangement, Disclosure [Abstract]
Prepaid Expense and Other Assets, Current [Abstract]
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Summary of Assumptions Used to Value Stock Options Granted
Schedule of loss from operations before income taxes
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Refund liability
Amount Of Refund Liability
Amount of refund liability.
Title and Position [Axis]
Property, Plant, and Equipment [Table]
Proceeds from Issuance of Warrants
Gross proceeds of warrants
Sale of Stock [Axis]
Entity Current Reporting Status
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Number of Shares, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Quoted Prices in Active Markets (Level 1) [Member]
Fair Value, Inputs, Level 1 [Member]
Class of Stock [Domain]
Class of Stock [Domain]
Accounts payable
Accounts Payable, Current
Summary of computation of diluted net loss per share attributable to common stockholders
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Financial Instrument [Axis]
Assets, Fair Value Disclosure, Total
Assets, Fair Value Disclosure
Other noncurrent assets
Increase (Decrease) in Other Noncurrent Assets
Issuance of Common Stock and Pre-Funded Warrants in Follow-On Financing, Shares
Issuance of Common Stock and Pre-Funded Warrants in Follow-On Financing, Shares
Issuance of common stock and pre-funded warrants in Follow-On Financing, Shares
Document Transition Report
Pre Funded Warrant [Table]
Pre Funded Warrant table
Commitments and Contingencies Disclosure [Abstract]
Disclousre Of Prepaid Expenses Other Current Assets and Other Noncurrent Assets [Text Block]
Disclousre of prepaid expenses other current assets and other noncurrent assets text block.
Prepaid Expenses and Other Current Assets
Current liabilities:
Liabilities, Current [Abstract]
Offering Price
Offering Price
Share-Based Payment Arrangement [Abstract]
Line of credit facility commitment fee amount
Line of Credit Facility, Commitment Fee Amount
Common Stock [Member]
Common Stock [Member]
Pre Funded Warrants TextBlock
Pre Funded Warrants TextBlock
Pre Funded Warrants
Statistical Measurement [Domain]
Lessee tenant improvement allowance
Incentive from Lessor
Prepaid expenses
Prepaid Expense, Current
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted-average common shares outstanding-basic
Weighted-average common shares - basic
Property, Plant, and Equipment [Abstract]
Assets [Abstract]
Assets
Recognized
Business Combination, Separately Recognized Transactions, Revenues and Gains Recognized
Payoff of venture debt
Payoff of Venture Debt
Payoff of Venture Debt
Entity Central Index Key
Recognized Remaining Vesting Terms
Recognized Remaining Vesting Terms
Recognized Remaining Vesting Terms
Accounting Policies [Table]
Accounting policies.
Antidilutive Securities [Axis]
Disclosure in tabular form of common stock shares reserved for future issuance.
Disclosure In Tabular Form Of Common Stock Shares Reserved For Future Issuance [Table]
Aggregate Intrinsic Value, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Class of Stock [Line Items]
Number of Common Stock Underlying Shares
Number of Common Stock Underlying Shares
Number of common stock underlying shares
Current Fiscal Year End Date
Debt and Warrant Issuance Costs
Debt, Policy [Policy Text Block]
Document Quarterly Report
Property and equipment additions included in accrued expenses and other liabilities
Property and Equipment Additions Included in Accrued Expenses and Other Liabilities
Property and Equipment Additions Included in Accrued Expenses and Other Liabilities
Accrued external research and development
Accrued Research And Development Expenses Current
Accrued research and development expenses current.
Proceeds from sale of equity method investments
Proceeds from Sale of Equity Method Investments
Common Stock, Number of Shares, Par Value and Other Disclosure [Abstract]
Property and Equipment include in Accounts Payable
Property and Equipment include in Accounts Payable
Property and equipment additions included in accounts payable
Lease Expiration Date
Lease expiration date
Two Thousand And Twenty And Two Thousand And Twenty Three Term A Loan [Member]
Two Thousand And Twenty And Two Thousand And Twenty Three Term A Loan [Member]
Two thousand and twenty and two thousand and twenty three term a loan.
Significant Other Observable Inputs (Level 2) [Member]
Fair Value, Inputs, Level 2 [Member]
Weighted- Average Exercise Price, Outstanding at Beginning Balance
Weighted- Average Exercise Price, Outstanding at Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Entity Incorporation, State or Country Code
Net loss per share - diluted
Net income (loss) per share-diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Shares issued during period
Sale of Stock, Number of Shares Issued in Transaction
Number of shares sold
Preferred Stock, Par or Stated Value Per Share
Preferred stock par value per share
Operating lease weighted average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Net income (loss)
Net loss and comprehensive loss
Net loss
Impairment, long-lived asset, held-for-use
Long-Lived Asset, Held and Used, Impairment Loss
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Long-Lived Tangible Asset
Long-Lived Asset, Class [Domain]
Restricted cash equivalents
Restricted Cash and Cash Equivalent, Noncurrent
Restricted Cash and Cash Equivalents, Noncurrent, Total
Restricted cash and restricted cash equivalents
Sales-based milestone
Sales Based Milestone [Member]
Sales based milestone.
Pre-funded Warrants [Member]
Pre-funded Warrants [Member]
Pre-funded warrants [Member]
Convertible notes
Convertible Notes [Policy Text Block]
Convertible notes.
Measurement Frequency
Measurement Frequency [Domain]
Two Thousand Seventeen Stock Option and Grant Plan [Member]
Two thousand seventeen stock option and grant plan.
2017 Stock Option and Grant Plan [Member]
Equity Components [Axis]
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Summary of prepaid expenses and other current assets table text block.
Summary Of Prepaid Expenses And Other Current Assets [Table Text Block]
Summary Of Prepaid Expenses And Other Current Assets
Agreements with Horizon
Collaborative Arrangement Disclosure [Text Block]
Statement of Cash Flows [Abstract]
Venture Debt Two Thousand Twenty And Two Thousand And Twenty Three Term A Loan [Member]
Venture debt two thousand twenty and two thousand and twenty three term a loan.
Venture Debt Two Thousand Twenty And Two Thousand And Twenty Three Term A Loan [Member]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Cash, Cash Equivalent, and Investment [Table Text Block]
Summary of Short Term Investments
Income Tax Disclosure [Abstract]
License Agreement With The University Of Colorado [Member]
License agreement with the university of colorado.
License Agreement With The University Of Colorado [Member]
Weighted- Average Exercise Price, Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Line of credit facility commitment fee percentage
Line of Credit Facility, Commitment Fee Percentage
Revenue Recognition
Revenue [Policy Text Block]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
ADX Zero Nine Seven [Member]
ADX Zero Nine Seven [Member]
ADX-097 Member]
Fair Value Measurements
Fair Value Disclosures [Text Block]
Restricted cash and cash equivalents
Restricted Cash and Cash Equivalent
Restricted Cash and Cash Equivalents, Total
Issuance of common stock in the pre-closing financing, Shares
Issuance of Common Stock During Period Pre-Closing Financing, Net of Issuance Costs
Issuance of Common Stock During Period Pre-Closing Financing, Net of Issuance Costs
Investments Disclosure Abstract
Investments Disclosure Abstract
Investments Disclosure [Abstract]
Chief Executive Officer [Member]
Period of obligation to pay royalties
Period Of Obligation To Pay Royalties
Period of obligation to pay royalties.
Preferred Stock, Shares Authorized
Preferred stock shares authorized
Mergers, Acquisitions and Dispositions Disclosures [Text Block]
Accounting for the Merger
Liabilities:
Operating Lease Liabilities Lessee [Abstract]
Operating lease liabilities lessee [Abstract].
Class of Stock [Axis]
Class of Stock [Axis]
Issuance Of Common Stock And Prefunded Warrants In Registered Direct Offering Shares
Issuance Of Common Stock And Prefunded Warrants In Registered Direct Offering Shares
Issuance of common stock and pre-funded warrants in Registered Direct Offering, net of issuance costs, Shares
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Options to purchase common stock
Share-Based Compensation Arrangements by Share-Based Payment Award, Restricted Stock Units, Vested and Expected to Vest [Table Text Block]
Company's RSU Activity
Percentage increase in initial annual base rent per square foot.
Lessee Operating Lease Not Yet Commenced Increase In Percentage Of Base Rent
Lessee operating lease not yet commenced increase in percentage of base rent.
Short Term Investments Acquired In reverse recapitalization
Short Term Investments Acquired In reverse recapitalization
Short Term Investments Acquired In reverse recapitalization
AOCI Attributable to Parent [Member]
Share based awards, shares available for future grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Stock-Based Compensation
Compensation Related Costs, Policy [Policy Text Block]
Deferred Transaction Costs
Deferred Charges, Policy [Policy Text Block]
Assets Not Yet In Use [Member]
Assets Not Yet In Use [Member]
Assets not yet in service [Member]
Preferred stock shares outsstanding
Ending balance, Shares
Temporary Equity, Shares Outstanding
Beginning balance, Shares
Segment Information
Segment Reporting, Policy [Policy Text Block]
Tabular disclosure of recapitalization of assets and liabilities.
Schedule of Recapitalization of Assets and Liabilities [Table Text Block]
Schedule of Recapitalization of Assets and Liabilities
Accrued expenses and other current liabilities
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Weighted- Average Exercise Price, Cancelled
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted- Average Exercise Price, Cancelled
Weighted- Average Exercise Price, Forfeited
Other Research and Development Expense
Other Research And Development Expense
Total accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Accrued Liabilities, Current
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Number of Shares, Outstanding at Beginning Balance
Number of Shares, Outstanding at Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Less current portion
Long-Term Debt, Current Maturities
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Document Type
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Liabilities and Equity [Abstract]
Liabilities and stockholders' equity
Equity Method Investment [Table]
Shares reserved for stock option exercises [Member]
Loss from operations
Operating Income (Loss)
Sale of stock issue price per share
Sale of Stock, Price Per Share
Common stock at a public offering
Marketable Securities, Policy [Policy Text Block]
Short-Term Investments
License Agreement With Bristol Mayers Equib Company [Member]
License Agreement With Bristol Mayers Equib Company [Member]
License agreement with bristol mayers equib company.
Defined Contribution Plan [Abstract]
Segment Reporting [Table]
Asset Class [Domain]
Entity File Number
Increase In Number Of Shares Reserved For Issuance Percent Of Common Stock Outstanding
Increase In Number Of Shares Reserved For Issuance Percent Of Common Stock Outstanding
Increase in number of shares reserved for issuance, percent of common stock outstanding
Lab equipment [Member]
Equipment [Member]
Schedule of Maturities of Operating Lease Liabilities
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Location, Statement of Income, Balance [Axis]
Risk-free interest rate range, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Impairment of Long-Lived Assets
Long-Lived Asset, Excluding Intangible Asset and Goodwill, Impairment and Disposal [Policy Text Block]
Accumulated Deficit [Member]
Retained Earnings [Member]
Share-Based Payment Arrangement, Employee [Member]
Share Based Payment Arrangement Employee [Member]
Reserved For Future Issuance Under Two Thousand And Twenty Four Employee Stock Purchase Plan [Member]
Reserved For Future Issuance Under Two Thousand And Twenty Four Employee Stock Purchase Plan [Member]
Shares reserved for future issuance under the 2024 Employee Stock Purchase Plan
Entity Registrant Name
Other Deferred Costs, Net
Other Deferred Costs, Net, Total
Deferred transaction costs
Lessee, operating lease, lease not yet commenced, renewal term
Lessee, Operating Lease, Lease Not yet Commenced, Renewal Term
Accounting Policies [Abstract]
Depreciation expense
Depreciation
Warrant, Exercise Price, Decrease
Warrant, Exercise Price, Decrease
Cash, Cash Equivalent, and Short-Term Investment [Text Block]
Short-Term Investments
Entity Address, Address Line One
Loan And Security Agreement With Silicon Valley Bank [Member]
Loan And Security Agreement With Silicon Valley Bank [Member]
Loan and security agreement with silicon valley bank.
Issuance of common stock from option exercises, Shares
Number of Shares, Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Proceeds from Issuance or Sale of Equity
Proceeds from Issuance or Sale of Equity, Total
Proceeds from Issuance or sale of equity
Proceeds from issuance of common stock and pre-funded warrants in Follow-On Financing, net of issuance costs
Weighted- Average Exercise Price, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Total current assets
Assets, Current
Furniture and fixtures [Member]
Furniture and Fixtures [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Net Loss per Share Attributable to Common Stockholders
Earnings Per Share, Policy [Policy Text Block]
Segments [Axis]
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Entity Small Business
Long-term debt, net
Long-Term Debt, Excluding Current Maturities
Beginning balance
Ending balance
Temporary Equity, Including Noncontrolling Interest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Aggregate Intrinsic Value, Vested and expected to vest
Investment, Name [Domain]
Research and Development Tax Incentive
Research and Development Tax Incentive [Policy Text Block]
Research and development tax incentive.
Unrecognised compensation cost
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Colorado License Agreement [Member]
Colorado License Agreement [Member]
Colorado License Agreement
Interest Income (Expense), Operating
Interest Income (Expense), Operating, Total
Interest income, net
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Business Contact [Member]
Accrued compensation and related expenses
Employee-related Liabilities, Current
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Investment in Equity Securities
Equity Method Investments and Joint Ventures Disclosure [Text Block]
Earnings Per Share [Abstract]
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Accrued Expenses and Other Current Liabilities
Accrued Expenses And Other Current Liabilities Disclosure [Text Block]
Accrued expenses and other current liabilities disclosure.
Shares sold received amount
Sale of Stock, Consideration Received Per Transaction
Plan Name [Axis]
Equity [Abstract]
Venture debt, net of current portion
Long-Term Line of Credit, Noncurrent
Product and Service [Domain]
Equity [Text Block]
Common Stock
Measurement Frequency
Measurement Frequency [Axis]
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Entity Tax Identification Number
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion of convertible preferred stock to common stock in connection with the Merge, Share
Equity Component [Domain]
Development and regulatory milestones
Development and Regulatory Milestones Receivable
Development and Regulatory Milestones Receivable
Entity Address, City or Town
Interest payments on venture debt
Capital Expenditures Incurred but Not yet Paid
Summary of the transaction price allocated to each performance obligation
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Table Text Block]
Segments [Domain]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Equity Method Investments
Equity method investments
Schedule of components of provision for income taxes
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Long Term Debt Percentage Bearing Annualy Prime Rate
Long Term Debt Percentage Bearing Annualy Prime Rate
Long term debt percentage bearing annual prime rate
Antidilutive Security, Excluded EPS Calculation [Table]
Proceeds from long term line of credit
Proceeds from borrowings under loan and security agreement, net
Proceeds from Long-Term Lines of Credit
Statement [Table]
Total lease costs
Lease, Cost, Total
Total stock-based compensation expense
Share-Based Payment Arrangement, Expense
Share-Based Payment Arrangement, Recognized Amount [Abstract]
Entity Shell Company
Expected term (years) range
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Net cash used in investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Statement [Line Items]
Accrued Expenses And Other Liabilities Current
Accrued Expenses And Other Liabilities Current
Accrued expenses and other current liabilities
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of Shares, Vested
Maximum [Member]
Maximum [Member]
Debt Disclosure [Abstract]
Sale of Stock [Domain]
Prepaid external research and development
Prepaid External Research And Development Current
Prepaid external research and development current.
Two Thousand Twenty Four Employee Stock Purchase Plan [Member]
Two Thousand Twenty Four Employee Stock Purchase Plan [Member]
2024 Employee Stock Purchase Plan [Member]
Address Type [Domain]
Net increase (decrease) in cash, cash equivalents, restricted cash and restricted cash equivalents
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Excluding Exchange Rate Effect, Including Discontinued Operation
Principles of Consolidation
Consolidation, Policy [Policy Text Block]
Subsequent Events [Abstract]
Related party transaction expense
Related Party Transaction, Purchases from Related Party
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Option, Increase for Cost Recognition
Asset Class [Axis]
Schedule of deferred taxes
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Discovery and Other [Member]
Discovery and Other [Member]
Discovery and other [Member]
Investments in Equity Securities
Equity Method Investments [Policy Text Block]
Current assets:
Assets, Current [Abstract]
Sale of Stock, Consideration Received on Transaction
Reverse recapitalization transaction costs
Related Party Transaction [Domain]
Revenue, Performance Obligation Satisfied over Time [Abstract]
Accrued professional services and other
Accrued Professional Fees And Other Accrued Liabilities Current
Accrued professional fees and other accrued liabilities current.
Document Fiscal Year Focus
Document Fiscal Year Focus
Common stock shares outstanding
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Security deposit
Security Deposit
Development and sales milestone payment payable
Development And Sales Milestone Payment Payable
Development and sales milestone payment payable.
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Financial Instruments [Domain]
Business Combination [Line Items]
Related Party
Related Party [Member]
Operating lease liabilities, net of current portion
Lease liability, net of current portion
Operating Lease, Liability, Noncurrent
Current:
Current Liabilities Lessee [Abstract]
Current liabilities lessee [Abstract].
Total minimum lease payments
Lessee, Operating Lease, Liability, to be Paid, Total
Total minimum lease payments
Security Exchange Name
Related and Nonrelated Parties [Axis]
Recent Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Warrants to purchase common stock [Member]
Shares reserved for warrants [Member]
Warrant [Member]
Class of warrants or rights exercise price per share
Class of Warrant or Right, Exercise Price of Warrants or Rights
Class of warrants or rights exercise price per share
Disclosure in tabular form of venture debt [Line Items]
Disclosure in tabular form of venture debt.
Entity Address, State or Province
Noncurrent:
Non Current Liabilities Lessee [Abstract]
Non current liabilities lessee [Abstract].
Unrecognised compensation cost, recognition period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Royalty as a percentage of sales
Royalty As A Percentage Of Net Sales
Royalty as a percentage of net sales.
Expected stock price volatility range, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Disclosure In Tabular Form Of Common Stock Shares Reserved For Future Issuance [Table Text Block]
Disclosure in tabular form of common stock shares reserved for future issuance.
Schedule of Shares of Common Stock for Future Issuance
Convertible Preferred Stock
Disclosure In Entirety Of Temporary Equity
Disclosure in entirety of temporary equity.
Operating lease right-of-use assets
Right-of-use asset, operating leases
Operating Lease, Right-of-Use Asset
Tranche Three [Member]
Tranche Three Milestone [Member]
Tranche three milestone.
Issuance of Common Stock Pursuant to At-the-Market Offering, Net of Discounts and Issuance Cost
Issuance of Common Stock Pursuant to At-the-Market Offering, Net of Discounts and Issuance Cost
Issuance of common stock pursuant to at-the-market offering, net of discounts and issuance costs
Amendment Flag
Stock-Based Compensation
Share-Based Payment Arrangement [Text Block]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Issuance of common stock to Homology shareholders in reverse recapitalization, Shares
Stock Issued During Period Value to Homology Shareholders in Reverse Recapitalization
Stock Issued During Period Value to Homology Shareholders in Reverse Recapitalization
Debt Instrument [Axis]
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other income (expense)
Other income
Cash, cash equivalents, restricted cash and restricted cash equivalents at beginning of period
Cash, cash equivalents, restricted cash and restricted cash equivalents at end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Total cash, cash equivalents, restricted cash and restricted cash equivalents
City Area Code
Convertible Preferred Stock
Convertible Preferred Stock [Policy Text Block]
Convertible preferred stock.
Stockholders' Equity Note, Spinoff Transaction
Reverse recapitalization transaction costs
Preferred Stock [Member]
Preferred Stock [Member]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Proceeds from issuance of common stock
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock and pre-funded warrants in Registered Direct Offering, net of issuance costs
Asset Acquisition [Abstract]
Stock issued during period shares purchase of assets
Stock Issued During Period, Shares, Purchase of Assets
Number of shares purchase
Proceeds from Sales of Business, Affiliate and Productive Assets
Amount received on sales of asset
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Operating expenses:
Operating Expenses [Abstract]
Computer equipment [Member]
Computer Equipment [Member]
Commercial Milestones Receivable
Commercial Milestones Receivable
Commercial milestones
Restricted Cash and Cash Equivalents [Axis]
Two Thousand Twenty Four Stock Option and Incentive Plan [Member]
Two Thousand Twenty Four Stock Option and Incentive Plan [Member]
2024 Stock Option and Incentive Plan [Member]
Due to related parties
Other Liabilities
Issuance Of CVR At Fair Value
Issuance Of CVR At Fair Value
Issuance of CVR at fair value
Common Stock, Par or Stated Value Per Share
Common stock, par value per share
Cash and Cash Equivalents [Abstract]
Weighted Average Remaining Contractual Term, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term
Leases
Lessee, Leases [Policy Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Number of shares, Vested and expected to vest
Rule 10b5-1 Arr Modified [Flag]
Rule 10b5-1 Arrangement Modified [Flag]
Rule 10b5-1 Arrangement Modified
Total current liabilities
Liabilities, Current
Horizon Therapeutics Ireland DAC
Horizon Therapeutics Ireland DAC Member
Horizon Therapeutics Ireland DAC [Member]
Leasehold improvements [Member]
Leasehold Improvements [Member]
Preferred stock liquidation preference
Temporary Equity, Liquidation Preference
Increase In Common Stock Capital Shares Reserved For Future Issuance
Increase In Common Stock Capital Shares Reserved For Future Issuance
Increase in number of shares reserved for issuance (shares)
Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization
Total property and equipment
Loan And Security Second Amendment Agreement With Silicon Valley Bank [Member]
Loan And Security Second Amendment Agreement With Silicon Valley Bank [Member]
Loan and security second amendment agreement with silicon valley bank.
Pre Funded Warrants [Line items]
Pre Funded Warrants [Line items]
Payments Less Certain Contractual Offsets
Payments Less Certain Contractual Offsets
Payments less certain contractual offsets
Variable lease costs
Variable Lease, Cost
Segment Reporting [Text Block]
Segment Reporting
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Trading Symbol
Geographical [Axis]
Amortization of Debt Issuance Costs and Discounts
Amortization of debt discount and issuance costs, net of accrued interest
Schedule of Property Plant and Equipment
Property, Plant, and Equipment [Table Text Block]
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Entity Emerging Growth Company
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Principal amount of term loans
Long-Term Debt, Gross
Plan Name [Domain]
Defined Contribution Plan
Defined Contribution Plan [Text Block]
US Treasury Securities [Member]
US Treasury securities
Business Combination [Table]
Series A convertible preferred stock [Member]
Series A convertible preferred stock [Member]
Series A Convertible Preferred Stock [Member]
Series A Convertible Preferred Stock.
Supplemental disclosure of non-cash operating, investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Cover [Abstract]
Summary of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents
Schedule of Cash and Cash Equivalents [Table Text Block]
Other segment items
Segment Reporting, Other Segment Item, Amount
Summary of Fair Value Measurement Significant Inputs
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Operating lease weighted average remaining lease term
Operating Lease, Weighted Average Remaining Lease Term
Oxb Solutions
Oxb Solutions [Member]
Oxb Solutions [Member]
Concentrations of Credit Risk and Significant Suppliers
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Cash FDIC insured amount
Cash, FDIC Insured Amount
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Additional paid-in capital
Additional Paid in Capital
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Fair Value Disclosures [Abstract]
Cash equivalents
Cash and Cash Equivalent
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Summary of Long-term Debt Balance
Disclosure In Tabular Form Of Venture Debt [Table Text Block]
Disclosure in tabular form of venture debt.
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by (used in) financing activities
Common stock at a public offering
Common Stock at a Public Offering
Common Stock at a Public Offering
Payables and Accruals [Abstract]
Proceeds from Stock Plans
Proceeds from issuance of common stock and pre-funded warrants in Follow-On Financing, net of issuance costs
Number of Shares, Cancelled
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number of Shares, Forfeited
Entity Filer Category
Debt Instrument, Name [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Weighted- Average Exercise Price, Vested and expected to vest
Issuance of Common Stock and Pre-Funded Warrants in Follow-On Financing
Issuance of Common Stock and Pre-Funded Warrants in Follow-On Financing
Issuance of common stock and pre-funded warrants in Follow-On Financing
Issuance of Common Stock and Pre-Funded Warrants in Private Placement, Net of Issuance Cost
Issuance of Common Stock and Pre-Funded Warrants in Private Placement, Net of Issuance Cost
Issuance of common stock and pre-funded warrants in private placement, net of issuance costs
Property and equipment, net
Property and equipment, net
Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization
Transaction as an asset sale
Increase (Decrease) in Asset, Held-for-Sale
Two Thousand And Twenty Term A Loan Advance [Member]
Two Thousand And Twenty Term A Loan Advance [Member]
Two thousand and twenty term a loan advance.
Sixth Amendment Agreement With Silicon Valley Bank [Member]
Sixth Amendment Agreement With Silicon Valley Bank [Member]
Sixth amendment agreement with silicon valley bank.
Beginning balance, Shares
Ending balance, Shares
Shares, Outstanding
Document Information [Line Items]
Segment Reporting [Abstract]
Schedule of reconciliation of income tax expense (benefit) computed
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Other
Other Assets, Current
Entity Address, Postal Zip Code
Statement of Financial Position [Abstract]
Local Phone Number