Committee Composition

Director Name Audit Committee Compensation Committee Nominating and Corporate Governance Committee Research and Development Committee
David Grayzel Member ofthe Research and development committee
Mark Iwicki Chairman of the Board Member of the Audit Committee Chairperson of the Compensation Committee
Kathleen LaPorte Financial Expert Chairperson of the Audit Committee Member of the Nominating and Corporate Governance Committee
Bill Lundberg, M.D. Member of the Compensation Committee Chairperson ofthe Research and development committee
Isaac Manke, Ph.D. Member of the Compensation Committee
Mary Thistle Member of the Audit Committee Chairperson of the Nominating and Corporate Governance Committee
Arthur Tzianabos, Ph.D. Member ofthe Research and development committee
Diyong Xu Member of the Nominating and Corporate Governance Committee
Legend = Chairperson = Member = Chairman of the Board = Financial Expert